Talk:Oncovirus

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DNA viruses

   * Human papilloma virus (HPV), a DNA virus, causes transformation in cells through interfering with tumor suppressor proteins such as p53. Interfering with the action of p53 allows a cell infected with the virus to move into a different stage of the cell cycle allowing the virus genome to be replicated forcing the cell into the S phase of the cell cycle could cause the cell to become transformed.[2] It increases risk of, e.g., cervical cancer.
   * Human herpes virus 8 is associated with Kaposi’s sarcoma, a type of skin cancer.[3]
   * Epstein-Barr virus (EBV) is associated with four types of cancers
   * Merkel cell polyomavirus - a polyoma virus - is strongly associated with the development of Merkel cell cancer - a rare form of skin cancer.[4]

[edit] RNA viruses

It is not only DNA viruses that are associated with cancers some RNA viruses have also been associated such as the Hepatitis C Virus as well as Human T cell leukaemia virus-1 (HTLV-1)

[edit] Overview table Virus Associated cancer types Hepatitis viruses, including hepatitis B and hepatitis C Hepatocellular carcinoma (liver cancer).[5][6] Human T-lymphotropic virus Tropical spastic paraparesis and adult T-cell leukemia[7] Human papillomaviruses Cancers of cervix, skin, anus and penis.[8] mouth, throat and maybe lung cancer. Kaposi’s sarcoma-associated herpesvirus Kaposi’s sarcoma and Body cavity lymphoma Epstein–Barr virus Burkitt’s lymphoma, Hodgkin’s lymphoma, B lymphoproliferative disease and Nasopharyngeal carcinoma.[9]

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